The 22 Sep 1917 issues of Motography, Moving Picture World, and Motion Picture News announced that actress-dancer Ann Pennington had recently started work on the production, following her successful season in the latest edition of the Ziegfeld Follies. The film was expected to require a great many background actors, mostly female. The star’s wardrobe reportedly featured “something new in the way of satin pajamas and bathing suits that were never made for the water.” The original story, reportedly written for Pennington by Frederic Chapin, was originally titled "The Glory of Gloriana," according to some sources.
       The 13 Oct 1917 Motion Picture News revealed that Pennington had selected several Follies chorus girls to appear in the film, only to discover that some were not interested in screen careers. After surveying the chorus for willing participants, she was able to gather a satisfactory cast of background actresses.
       The 24 Nov 1917 Motion Picture News noted that the film’s antagonist, “Gordon Trent” played by Crauford Kent, was named after a columnist for New York City’s Morning Telegraph newspaper. The real-life Trent was reportedly as disreputable as his screen counterpart. An article in the 8 Apr 1916 Moving Picture World credited publicist Joseph W. Farnum as a contributor to the column.
       The Dec 1917 Photo-Play Journal claimed that Pennington performed her own stunts in the picture, such as diving and climbing down “dangerous walls in truly death-defying fashion.” Production was nearly completed by 29 Sep 1917, as stated in that day’s Moving Picture World.
       Various sources have noted that some location scenes were shot in Garden City, Long Island, NY, with the St. Paul's School football team.
       The film was scheduled to open on 5 Nov 1917, one week after its scheduled release date, according to the 27 Oct 1917 Motion Picture News and Moving Picture World. The delay was attributed to the star falling ill, and to the time required for the construction of elaborate sets, such as a Japanese tea room. Production took place at the Famous Players 56th Street Studios in New York City. A 15 Nov 1917 release date was listed in the 22 Dec 1917 Moving Picture World.
       The Antics of Ann opened to generally positive reviews. Box-office reports in the 22 Dec 1917 Motion Picture News indicated that the film was performing well, particularly in the northern and eastern U.S.