Bill Carver, an innocent man who has been framed by gangster Joe Mallon, is forced to participate in a jailbreak engineered by Mallon. Mallon and his henchmen are recaptured by the police, but Bill, accompanied by his dog Wolf, escapes to the Arizona desert, where he is befriended by Dr. Harkness and his daughter Linda. Bill's idyllic existence is threatened when Mallon breaks jail again and implicates Bill in a bank holdup. Realizing that the only way he can clear his name is to force a confession from Mallon, Bill follows the gangsters' trail to the desert, where he encounters Mallon and his henchmen. Lost in the arid wilderness, the fugitives' only hope is to reach the border with Bill and his dog guiding them. Tormented by hungry wolves and blistering heat, Mallon kills Blimp and Mike, two of his gang, in a fight over water. Later, in a struggle over the canteen, Mallon kills Marty, another gang member, leaving only him and Bill to stagger on. Bill taunts Mallon and refuses to continue unless the gangster signs a confession clearing him of all charges. Desperate, Mallon agrees and as he finishes writing the document, Dr. Harkness and Linda arrive in their car. Furious, Mallon tries to shoot Bill, but the loyal Wolf drags him down. With his name cleared and the money returned, Bill is free to return to a peaceful life with Linda and the doctor.